B.Pharm 4th Semester Pharmaceutical Pharmacology 1 Notes

Radhe Radhe, B.Pharm students! In this post, you will find the notes for your 4th semester Pharmaceutical Pharmacology 1 subject . Here you will find notes, books, previous year questions (PYQs), and important question-answers related to your pharmacy course Syllabus. You will also find GPAT updates here. Here You will find pharmacy-related vacancies, so stay calm and connected with Pulse by Anubhav. Join Our Telegram Channel As Well As Bookmark Our Site For Latest Stuff.

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As you may have realized, pursuing a B.Pharm degree is not easy. Many people initially choose it as just one option, but later they discover how much studying is involved. Your B.Pharm course is divided into 8 semesters. In the fourth semester, you have to study a total number of 5 subjects, of which all are compulsory. You won’t have to study any additional subjects in this semester.

The pharmacy field is a very important medical field. Here, pharmacists not only dispense medication to patients but also educate them about the medicines. In the pharmaceutical industry, these same pharmacists manufacture the medicines and conduct research on them.

The link to download notes for all units is given below. If you want to download the PDF without reading the post, you can download the PDF by clicking on the link given below. You can also join our Telegram channel for future updates.

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The Subjects in the 4th semester of B.Pharm are:

  • Pharmaceutical Organic Chemistry – 3
  • Physical Pharmaceutics – 2
  • Medicinal Chemistry – 1
  • Pharmacology – 1
  • Pharmacognosy and Phytochemistry – 1

Pharmaceutical Pharmacology 1 is divided into three parts and will be taught from the 4th to the 6th semester. It’s a very interesting subject. In this subject, you will learn about diseases and human physiology, and how different diseases are treated.

B.Pharm 4th Semester Pharmaceutical Pharmacology 1 Syllabus

Before downloading the notes, please take a look at the Pharmaceutical Pharmacology 1 syllabus to understand what topics are covered.

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UNIT – I

General Pharmacology

a. Introduction to Pharmacology

  • Definition of pharmacology
  • Historical landmarks and scope of pharmacology
  • Nature and sources of drugs
  • Essential drugs concept
  • Routes of drug administration
  • Agonists and antagonists
    • Competitive antagonists
    • Non-competitive antagonists
  • Spare receptors
  • Drug related terms:
    • Addiction
    • Tolerance
    • Dependence
    • Tachyphylaxis
    • Idiosyncrasy
    • Drug allergy

b. Pharmacokinetics

  • Membrane transport
  • Absorption of drugs
  • Distribution of drugs
  • Metabolism of drugs
  • Excretion of drugs
  • Enzyme induction
  • Enzyme inhibition
  • Kinetics of drug elimination

UNIT – II

General Pharmacology

a. Pharmacodynamics

  • Principles and mechanisms of drug action
  • Receptor theories
  • Classification of receptors
  • Regulation of receptors
  • Drug–receptor interactions
  • Signal transduction mechanisms:
    • G-protein coupled receptors
    • Ion channel receptors
    • Transmembrane enzyme-linked receptors
    • JAK-STAT binding receptors
    • Receptors regulating transcription factors
  • Dose–response relationship
  • Therapeutic index
  • Combined effects of drugs
  • Factors modifying drug action

b. Adverse Drug Reactions (ADR)

c. Drug Interactions

  • Pharmacokinetic drug interactions
  • Pharmacodynamic drug interactions

d. Drug Discovery & Clinical Evaluation

  • Drug discovery phase
  • Pre-clinical evaluation phase
  • Clinical trial phase
  • Phases of clinical trials
  • Pharmacovigilance

UNIT – III

Pharmacology of Drugs Acting on Peripheral Nervous System

a. Autonomic Nervous System (ANS)

  • Organization of ANS
  • Functions of ANS

b. Neurohumoral Transmission

  • Neurohumoral transmission
  • Co-transmission
  • Classification of neurotransmitters

c. Drugs Acting on ANS

  • Parasympathomimetics
  • Parasympatholytics
  • Sympathomimetics
  • Sympatholytics

d. Neuromuscular Blocking Agents

  • Neuromuscular blocking agents
  • Peripheral skeletal muscle relaxants

e. Local Anesthetic Agents

f. Drugs Used in

  • Myasthenia gravis
  • Glaucoma

UNIT – IV

Pharmacology of Drugs Acting on Central Nervous System

a. Neurohumoral Transmission in CNS

  • Role and importance of neurotransmitters:
    • GABA
    • Glutamate
    • Glycine
    • Serotonin
    • Dopamine

b. General Anesthetics & Pre-anesthetics

c. Sedatives, Hypnotics & Centrally Acting Muscle Relaxants

d. Anti-epileptic Drugs

e. Alcohols & Disulfiram


UNIT – V

Pharmacology of Drugs Acting on Central Nervous System

a. Psychopharmacological Agents

  • Antipsychotics
  • Antidepressants
  • Anti-anxiety agents
  • Anti-manic agents
  • Hallucinogens

b. Drugs Used in

  • Parkinson’s disease
  • Alzheimer’s disease

c. CNS Stimulants & Nootropics

d. Opioid Analgesics & Antagonists

e. Drug Dependence

  • Drug addiction
  • Drug abuse
  • Tolerance
  • Dependence

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B.Pharm 4th Semester Pharmaceutical Pharmacology 1 Notes PDF

💊 Download B.Pharm 4th Semester – Pharmaceutical Pharmacology-I Notes (Unit-wise | Flowchart PDF)

UNIT I — General Pharmacology (Pharmacokinetics)
📥 Introduction to Pharmacology & Pharmacokinetics Flowcharts
UNIT II — General Pharmacology (Pharmacodynamics)
📥 Drug Action, Receptors, ADR & Drug Interactions Flowcharts
UNIT III — Drugs Acting on Peripheral Nervous System
📥 ANS, Autacoids, Local Anesthetics & NMJ Blockers Flowcharts
UNIT IV — Drugs Acting on Central Nervous System
📥 CNS Neurotransmitters, Anesthetics & Antiepileptics Flowcharts
UNIT V — Psychopharmacology & Opioids
📥 Antipsychotics, Antidepressants, Opioids & Drug Dependence Flowcharts

⚡ Pharmaceutical Pharmacology-I notes are prepared in simple, exam-oriented flowchart format for quick revision, concept clarity & university exams.

🚀 Join Pulse Pharma Notes Telegram Channel 📘 Download Complete Pharmacology-I Flowchart Notes
🔗 Direct Flowchart Notes Access
📥 Click Here to Open Pharmacology-I Flowchart Notes

Also Read:- B.Pharm 4th Semester Pharmaceutical Physical Pharmaceutics 2 Notes

B.Pharm 4th Semester Pharmaceutical Pharmacology 1 Book PDF

Books are very important; you should definitely check out the books according to your syllabus. During your pharmacy studies, books from Nirali Prakashan and PV Sindhu are very helpful. You can download the PDFs from the link below.

  • Pharmaceutical Pharmacology 1 Nirali Prakashan Full Book PDF:- PDF
  • Pharmaceutical Pharmacology 1 Chemistry PV Sindhu Full Book PDF:- PDF
  • Pharmaceutical Pharmacology 1 Chemistry Thakur Publication Full Book PDF:- PDF
  • Pharmaceutical Pharmacology 1 Chemistry The Point Publication Full Book PDF: PDF

❓ Pharmaceutical Pharmacology-I – Frequently Asked Questions (B.Pharm 4th Semester)

What is Pharmaceutical Pharmacology-I?

Pharmaceutical Pharmacology-I deals with the study of drug action, pharmacokinetics, pharmacodynamics and drugs acting on peripheral and central nervous systems. It builds the foundation of clinical pharmacology.

Which topics are covered under General Pharmacology?

General Pharmacology includes introduction to pharmacology, pharmacokinetics, pharmacodynamics, drug–receptor interactions, adverse drug reactions, drug interactions and drug discovery.

Why is pharmacokinetics important in Pharmacology-I?

Pharmacokinetics explains absorption, distribution, metabolism and excretion of drugs, which helps in understanding dose, duration of action and drug interactions.

What is pharmacodynamics and why is it important?

Pharmacodynamics deals with mechanisms of drug action, receptor theories, dose–response relationship and therapeutic index, which are highly exam-oriented topics.

Which receptors are studied in Pharmacology-I?

G-protein coupled receptors, ion channel receptors, enzyme-linked receptors, JAK-STAT receptors and receptors regulating transcription factors are included.

What is the importance of ADR and drug interactions?

Adverse drug reactions and drug interactions help in understanding drug safety, rational use of medicines and prevention of harmful effects in clinical practice.

Which drugs are covered under Peripheral Nervous System?

Drugs acting on ANS such as parasympathomimetics, parasympatholytics, sympathomimetics, sympatholytics, neuromuscular blockers and local anesthetics are covered.

What topics are included under CNS pharmacology?

CNS pharmacology includes neurotransmitters, general anesthetics, sedatives, hypnotics, anti-epileptics, psychopharmacological agents and opioid analgesics.

Why are psychopharmacological drugs important?

Psychopharmacological drugs like antipsychotics, antidepressants and anti-anxiety agents are clinically important and frequently asked in university exams.

How to score well in Pharmacology-I exams?

Focus on flowcharts, classification tables, mechanisms of action, therapeutic uses, adverse effects and short notes for high scoring answers.

B.Pharm 4th Semester Notes

Subject NameNotes Link
Pharmaceutical Organic Chemistry – III Notes View Notes
Pharmaceutical Physical Pharmaceutics – II Notes View Notes
Pharmaceutical Medicinal Chemistry – I Notes View Notes
Pharmaceutical Pharmacology – I Notes View Notes
Pharmacognosy and Phytochemistry – I Notes View Notes

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