B.Pharm 2nd Semester Biochemistry Notes

Radhe Radhe, B.Pharm students! In this post, you will find the notes for your 2nd semester Biochemistry subject . Here you will find notes, books, previous year questions (PYQs), and important question-answers related to your pharmacy course. You will also find GPAT updates here. You will find pharmacy-related vacancies here, so stay calm and connected with Pulse by Anubhav. Join Our Telegram Channel As Well As Bookmark Our Site For Latest Update.

As you may have realized, pursuing a B.Pharm degree is not easy. Many people initially choose it as just one option, but later they discover how much studying is involved. Your B.Pharm course is divided into 8 semesters. In the second semester, you have to study a total of 6 subjects, of which 4 are compulsory. This semester you will be studying Computer Applications and Environmental Science. You will be taught this as an additional subject and you have to give it as a non-university paper.

The pharmacy field is a very important medical field. Here, pharmacists not only dispense medication to patients but also educate them about the medicines. In the pharmaceutical industry, these same pharmacists manufacture the medicines and conduct research on them.

Biochemistry is an important branch of pharmaceuticals that will also help you in your higher studies. You will need to pay special attention to it. You can take the GATE exam and pursue a master’s degree in Biochemistry. In This Semester You will only be taught a very small percentage of pharmaceutical biochemistry topics during your undergraduate studies.

The link to download notes for all units is given below. If you want to download the PDF without reading the post, you can download the PDF by clicking on the link given below. You can also join our Telegram channel for future updates.

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The Subjects in the 2nd semester of B.Pharm are:

• Human Anatomy and Physiology II
• Pharmaceutical Organic Chemistry I
• Pathophysiology
• Biochemistry
• Computer Applications
• Environmental Science

B.Pharm 2nd Semester Biochemistry Syllabus

Before downloading the notes, please take a look at the Biochemistry syllabus to understand what topics are covered.

UNIT I – Biomolecules & Bioenergetics 

Biomolecules

• Introduction, classification, chemical nature & biological role of:
  • Carbohydrates
  • Lipids
  • Nucleic acids
  • Amino acids & Proteins

Bioenergetics

• Concept of free energy
• Endergonic & exergonic reactions
• Relationship between free energy, enthalpy & entropy
• Redox potential
• Energy-rich compounds: classification & biological significance
• Biological significance of ATP & cyclic AMP (cAMP)

UNIT II – Carbohydrate Metabolism & Biological Oxidation 

Carbohydrate Metabolism

• Glycolysis: pathway, energetics & significance
• Citric Acid Cycle (TCA): pathway, energetics & significance
• HMP shunt & its significance
• Glucose-6-phosphate dehydrogenase (G6PD) deficiency
• Glycogen metabolism: pathways & glycogen storage diseases (GSD)
• Gluconeogenesis: pathway & significance
• Hormonal regulation of blood glucose level
• Diabetes mellitus

Biological Oxidation

• Electron Transport Chain (ETC) & its mechanism
• Oxidative phosphorylation & its mechanism
• Substrate-level phosphorylation
• Inhibitors of ETC & oxidative phosphorylation
• Uncouplers

UNIT III – Lipid & Amino Acid Metabolism 

Lipid Metabolism

• Oxidation of saturated fatty acid (Palmitic acid)
• Formation & utilization of ketone bodies
• Ketoacidosis
• De novo synthesis of fatty acids (Palmitic acid)
• Biological significance of cholesterol
• Conversion of cholesterol into:
  • Bile acids
  • Steroid hormones
  • Vitamin D
• Disorders of lipid metabolism:
  • Hypercholesterolemia
  • Atherosclerosis
  • Fatty liver
  • Obesity

Amino Acid Metabolism

• General reactions:
  • Transamination
  • Deamination
  • Decarboxylation
• Urea cycle & its disorders
• Catabolism of phenylalanine & tyrosine
• Metabolic disorders:
  • Phenylketonuria
  • Albinism
  • Alkaptonuria
  • Tyrosinemia
• Synthesis & significance of biological substances:
  • 5-HT (Serotonin)
  • Melatonin
  • Dopamine
  • Noradrenaline
  • Adrenaline
• Catabolism of heme
• Hyperbilirubinemia & jaundice

UNIT IV – Nucleic Acid Metabolism & Genetic Information Transfer 

• Biosynthesis of purine & pyrimidine nucleotides
• Catabolism of purine nucleotides
• Hyperuricemia & Gout
• Organization of mammalian genome
• Structure & functions of DNA & RNA
• DNA replication (semi-conservative model)
• Transcription (RNA synthesis)
• Genetic code
• Translation (Protein synthesis) & inhibitors

UNIT V – Enzymes

• Introduction & properties of enzymes
• Nomenclature & IUB classification
• Enzyme kinetics:
  • Michaelis–Menten plot
  • Lineweaver–Burk plot
• Enzyme inhibitors with examples
• Regulation of enzymes:
  • Enzyme induction & repression
  • Allosteric enzyme regulation
• Therapeutic & diagnostic applications of enzymes & isoenzymes
• Coenzymes: structure & biochemical functions

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B.Pharm 2nd Semester Biochemistry Notes PDF

Also Read:- B.Pharm 2nd Semester Pharmaceutical Organic Chemistry I Notes

B.Pharm 2nd Semester Biochemistry Book PDF

Books are very important; you should definitely check out the books according to your syllabus. During your pharmacy studies, books from Nirali Prakashan and PV Sindhu are very helpful. You can download the PDFs from the link below.

• Pharmaceutical Biochemistry Nirali Prakashan Full Book PDF:- PDF
• Pharmaceutical Biochemistry Chemistry PV Sindhu Full Book PDF:- PDF
• Pharmaceutical Biochemistry Chemistry Thakur Publication Full Book PDF:- PDF
• Pharmaceutical Biochemistry Chemistry The Point Publication Full Book PDF: PDF

B.Pharm 2nd Semester Notes