Radhe Radhe, B.Pharm students! In this post, you will find the notes for your 3rd semester Pharmaceutical Organic Chemistry -2 subject . Here you will find notes, books, previous year questions (PYQs), and important question-answers related to your pharmacy course. You will also find GPAT updates here. You will find pharmacy-related vacancies here, so stay calm and connected with Pulse by Anubhav. Join Our Telegram Channel As Well As Bookmark Our Site For Latest Stuff.

As you may have realized, pursuing a B.Pharm degree is not easy. Many people initially choose it as just one option, but later they discover how much studying is involved. Your B.Pharm course is divided into 8 semesters. In the third semester, you have to study a total of 4 subjects, of which all are compulsory. You won’t have to study any additional subjects this semester. You will meet new friends in this semester. There will be lateral entry for D.Pharma students in your class in this semester.
The pharmacy field is a very important medical field. Here, pharmacists not only dispense medication to patients but also educate them about the medicines. In the pharmaceutical industry, these same pharmacists manufacture the medicines and conduct research on them.
The link to download notes for all units is given below. If you want to download the PDF without reading the post, you can download the PDF by clicking on the link given below. You can also join our Telegram channel for future updates.
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The Subjects in the 3rd semester of B.Pharm are:
- Pharmaceutical Organic Chemistry -2
- Pharmaceutical Microbiology
- Physical Pharmaceutics -1
- Pharmaceutical Engineering
Pharmaceutical Organic Chemistry -2 is an important subject in the 3rd semester that continues from the organic chemistry covered in the 2nd semester. In this semester, you will have to study about many different reactions.
B.Pharm 3rd Semester Pharmaceutical Organic Chemistry -2 Syllabus
Before downloading the notes, please take a look at the Pharmaceutical Organic Chemistry -2 syllabus to understand what topics are covered.

UNIT I — Benzene and its derivatives
A. Structure of Benzene
- Analytical, synthetic and other evidences for benzene structure
- Orbital picture of benzene
- Resonance in benzene
- Aromatic characters
- Huckel’s rule
B. Reactions of Benzene
- Nitration
- Sulphonation
- Halogenation (reactivity)
- Friedel–Crafts alkylation — reactivity & limitations
- Friedel–Crafts acylation
C. Substituted Benzene
- Effect of substituents on reactivity
- Orientation in electrophilic substitution
- Mono-substituted benzene compounds
D. Structures & Uses
- DDT
- Saccharin
- BHC
- Chloramine
UNIT II — Phenols, Aromatic Amines & Aromatic Acids
Phenols
- Acidity of phenols
- Effect of substituents on acidity
- Qualitative tests
- Structure & uses of:
- Phenol
- Cresols
- Resorcinol
- Naphthols
Aromatic Amines
- Basicity of amines
- Effect of substituents on basicity
- Synthetic uses of aryl diazonium salts
Aromatic Acids
- Acidity of benzoic acid
- Effect of substituents on acidity
- Important reactions of benzoic acid
UNIT III — Fats and Oils (30 Hours total)
a. Fatty acids
- Reactions of fatty acids
b. Chemical processes of oils
- Hydrolysis
- Hydrogenation
- Saponification
- Rancidity of oils
- Drying oils
c. Analytical constants (very important)
- Acid value
- Saponification value
- Ester value
- Iodine value
- Acetyl value
- Reichert–Meissl (RM) value
→ Significance & principle of determination
UNIT IV — Polynuclear Hydrocarbons
a. Synthesis & reactions
b. Structure & medicinal uses of:
- Naphthalene
- Phenanthrene
- Anthracene
- Diphenylmethane
- Triphenylmethane
- Their derivatives
UNIT V — Cycloalkanes
Stability theories
- Baeyer’s strain theory
- Limitations of Baeyer’s theory
- Coulson & Moffitt’s modification
- Sachse–Mohr theory (Theory of strain-less rings)
Reactions (only these two)
- Cyclopropane
- Cyclobutane
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B.Pharm 3rd Semester Pharmaceutical Organic Chemistry -2 Notes PDF
🧪 Download B.Pharm 3rd Semester – Pharmaceutical Organic Chemistry-II Notes (Unit-wise | Flowchart PDF)
⚡ All Pharmaceutical Organic Chemistry-II notes are prepared in **simple flowchart format** for quick revision & exams.
🚀 Join Pulse Pharma Notes Telegram Channel 📘 Download Complete POC-II Flowchart Notes PackageAlso Read:- B.Pharm 2nd Semester Environmental Science Notes
B.Pharm 3rd Semester Pharmaceutical Organic Chemistry -2 Book PDF
Books are very important; you should definitely check out the books according to your syllabus. During your pharmacy studies, books from Nirali Prakashan and PV Sindhu are very helpful. You can download the PDFs from the link below.
- Pharmaceutical Organic Chemistry -2 Nirali Prakashan Full Book PDF:- PDF
- Pharmaceutical Organic Chemistry -2 Chemistry PV Sindhu Full Book PDF:- PDF
- Pharmaceutical Organic Chemistry -2 Chemistry Thakur Publication Full Book PDF:- PDF
- Pharmaceutical Organic Chemistry -2 Chemistry The Point Publication Full Book PDF: PDF
❓ Pharmaceutical Organic Chemistry–II (POC-II) – FAQs
What is Pharmaceutical Organic Chemistry–II?
POC-II is a B.Pharm 3rd semester core subject that covers aromatic chemistry, phenols, fats and oils, polynuclear hydrocarbons, and cycloalkanes with pharmaceutical and medicinal relevance.
Which unit is most important in POC-II?
UNIT I (Benzene & derivatives) and UNIT III (Fats and Oils) are most frequently asked in university exams and carry high weightage.
Are flowchart notes useful for POC-II?
Yes. Flowchart notes simplify reaction mechanisms, analytical values, and theories, making revision faster and exam answers more structured.
What should I focus on for UNIT III?
Focus on Saponification, Rancidity, Drying oils, and all analytical constants like Acid value, Iodine value, and RM value with their significance.
Where can I get POC-II flowchart notes?
You can download complete unit-wise POC-II flowchart notes from the Pulse Pharma Notes Telegram channel.