Radhe Radhe, B.Pharm students! In this post, you will find the notes for your 6th semester Biopharmaceutics & Pharmacokinetics subject . Here you will find notes, books, previous year questions (PYQs), and important question-answers related to your pharmacy course Syllabus. You will also find GPAT updates here and exam tips. Here You will find pharmacy-related vacancies, so stay calm and connected with Pulse by Anubhav. Join Our Telegram Channel As Well As Bookmark Our Site For Latest Update.
As you may have realized, pursuing a B.Pharm degree is not easy. Many people initially choose it as just one option, but later they discover how much studying is involved. Your B.Pharm course is divided into 8 semesters. In which the sixth semester, you have to study a total number of 6 subjects, of which all are compulsory. You won’t have to study any additional subjects in this semester.
The pharmacy field is a very important medical field. Here, pharmacists not only dispense medication to patients but also educate them about the medicines. In the pharmaceutical industry, these same pharmacists manufacture the medicines and conduct research on them.
The link to download notes for all units is given below. If you want to download the PDF without reading the post, you can download the PDF by clicking on the link given below. You can also join our Telegram channel for future updates.
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The Subjects in the 6th semester of B.Pharm are:
- 🧪 Medicinal Chemistry – III
- 💊 Pharmacology – III
- 🌿 Herbal Drug Technology
- 🧪 Biopharmaceutics & Pharmacokinetics
- 🧫 Pharmaceutical Biotechnology
- ✅ Pharmaceutical Quality Assurance
Biopharmaceutics & Pharmacokinetics is a very complex subject and is very difficult to remember. You will have to read about Biopharmaceutics & Pharmacokinetics Flow Properties.
B.Pharm 6th Semester Biopharmaceutics & Pharmacokinetics Syllabus
Before downloading the notes, please take a look at the Biopharmaceutics & Pharmacokinetics syllabus to understand what topics are covered.
✅ UNIT – I
Introduction to Biopharmaceutics & Absorption
- Biopharmaceutics – Introduction
- Mechanisms of drug absorption through GIT
- Factors influencing drug absorption through GIT
- Absorption of drugs from non-per oral extra-vascular routes
Distribution
- Tissue permeability of drugs
- Binding of drugs
- Apparent volume of distribution
- Plasma and tissue protein binding of drugs
- Factors affecting protein-drug binding
- Kinetics of protein binding
- Clinical significance of protein binding of drugs
✅ UNIT – II
Elimination
- Drug metabolism and basic understanding of metabolic pathways
- Renal excretion of drugs
- Factors affecting renal excretion
- Renal clearance
- Non-renal routes of drug excretion
Bioavailability & Bioequivalence
- Definition and objectives of bioavailability
- Absolute and relative bioavailability
- Measurement of bioavailability
- In-vitro drug dissolution models
- In-vitro – in-vivo correlation (IVIVC)
- Bioequivalence studies
- Methods to enhance dissolution rate and bioavailability of poorly soluble drugs
✅ UNIT – III
Pharmacokinetics
- Definition and introduction
- Compartment models
- Non-compartment models
- Physiological models
- One compartment open model:
- Intravenous injection (bolus)
- Intravenous infusion
- Extra-vascular administration
Pharmacokinetic Parameters
- KE (Elimination rate constant)
- t½ (Half-life)
- Vd (Volume of distribution)
- AUC (Area under curve)
- Ka (Absorption rate constant)
- Clt (Total clearance)
- CLR (Renal clearance)
- Methods of elimination and their significance & application
✅ UNIT – IV
Multicompartment Models
- Two compartment open model (IV bolus)
- Kinetics of multiple dosing
- Steady state drug levels
- Calculation of loading dose and maintenance dose
- Clinical significance in therapeutic settings
✅ UNIT – V
Nonlinear Pharmacokinetics
- Introduction
- Factors causing non-linearity
- Michaelis–Menten method for parameter estimation
- Explanation with drug examples
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B.Pharm 6th Semester Biopharmaceutics & Pharmacokinetics Notes PDF
🧪 Download B.Pharm 6th Semester – Biopharmaceutics & Pharmacokinetics Notes (PCI Syllabus | Unit-wise | Flowchart PDF)
⚡ Biopharmaceutics & Pharmacokinetics notes are prepared in simple exam-oriented flowchart format specially for AKTU / AV 6th Semester students – quick revision & high scoring.
🚀 Join Pulse Pharma Notes Telegram Channel 📘 Download Complete Biopharmaceutics & Pharmacokinetics Flowchart Notes (PDF)Also Read:- B.Pharm 6th Semester Herbal Drug Technology Notes
B.Pharm 6th Semester Biopharmaceutics & Pharmacokinetics Book PDF
Books are very important; you should definitely check out the books according to your syllabus. During your pharmacy studies, books from Nirali Prakashan and PV Sindhu are very helpful. You can download the PDFs from the link below.
- Pharmaceutical Biopharmaceutics & Pharmacokinetics Nirali Prakashan Full Book PDF:- PDF
- Pharmaceutical Biopharmaceutics & Pharmacokinetics Chemistry PV Sindhu Full Book PDF:- PDF
- Pharmaceutical Biopharmaceutics & Pharmacokinetics Chemistry Thakur Publication Full Book PDF:- PDF
- Pharmaceutical Biopharmaceutics & Pharmacokinetics Chemistry The Point Publication Full Book PDF: PDF
❓ Pharmaceutical Biopharmaceutics & Pharmacokinetics FAQs (B.Pharm 6th Semester)
❓ Biopharmaceutics & Pharmacokinetics FAQs (B.Pharm 6th Semester – AV Syllabus)
What is Biopharmaceutics & Pharmacokinetics in B.Pharm 6th Semester?
Biopharmaceutics & Pharmacokinetics deals with drug absorption, distribution, metabolism, excretion and the mathematical study of drug concentration in the body. It explains how drugs move in the body and helps in dose calculation and therapeutic effectiveness.
What topics are covered in UNIT-I?
UNIT-I includes introduction to biopharmaceutics, mechanisms of drug absorption through GIT, factors affecting absorption, drug distribution, tissue permeability, volume of distribution, plasma protein binding, kinetics of protein binding and clinical significance.
What is included in UNIT-II?
UNIT-II covers drug elimination including metabolism, renal excretion, renal clearance, non-renal excretion, bioavailability, bioequivalence studies, in-vitro dissolution models, in-vitro in-vivo correlation and methods to enhance bioavailability of poorly soluble drugs.
What does UNIT-III contain?
UNIT-III explains pharmacokinetics basics, compartment models, non-compartment models, physiological models, one compartment open model (IV bolus, infusion and extra-vascular administration) and pharmacokinetic parameters like half-life, AUC, clearance and volume of distribution.
What topics are covered in UNIT-IV?
UNIT-IV includes multicompartment models such as two compartment open model, kinetics of multiple dosing, steady state drug concentration, calculation of loading dose and maintenance dose and their clinical significance.
What is taught in UNIT-V?
UNIT-V focuses on nonlinear pharmacokinetics, factors causing non-linearity, Michaelis–Menten kinetics and estimation of pharmacokinetic parameters with drug examples.
Why is Biopharmaceutics & Pharmacokinetics important for exams?
This subject is scoring because it includes numerical concepts, definitions and models. Understanding drug absorption, clearance, half-life and dose calculation helps in writing structured and diagram-based answers in exams.
How to prepare Biopharmaceutics & Pharmacokinetics for AV exams?
Focus on compartment models, pharmacokinetic parameters, bioavailability concepts and dose calculations. Study flowcharts, definitions and formulas regularly for quick revision and better exam performance.
B.Pharm 6th Semester Notes
| Subject Name | Notes Link |
|---|---|
| 🧪 Medicinal Chemistry – III | View Notes |
| 💊 Pharmacology – III | View Notes |
| 🌿 Herbal Drug Technology | View Notes |
| 🧪 Biopharmaceutics & Pharmacokinetics | View Notes |
| 🧫 Pharmaceutical Biotechnology | View Notes |
| ✅ Pharmaceutical Quality Assurance | View Notes |
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